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PPP1R7 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501727356 Shop All Proteintech Group Inc Products
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50-172-7356 150 μL
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Catalog No. 50-172-7356 Supplier Proteintech Group Inc Supplier No. 116641AP150UL
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Rabbit Polyclonal Antibody

In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase 1 (PP1) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit, and a catalytic subunit. Sds22, also known as PPP1R7 (protein phosphatase 1, regulatory (inhibitor) subunit 7), is a 360 amino acid protein that localizes to the nucleus and contains ten LRR (leucine rich) repeats. Expressed in a variety of tissues, Sds22 functions as a regulatory subunit of the PP1 complex, suggesting a role in protein regulation throughout the cell. Multiple isoforms of Sds22 exist due to alternative splicing events.

Specifications

Antigen PPP1R7
Applications Western Blot
Classification Polyclonal
Concentration 0.13 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PPP1R7
Gene Accession No. Q15435, Q3UM45
Gene Alias PPP1R7, SDS22
Gene Symbols PPP1R7
Host Species Rabbit
Immunogen PPP1R7 Fusion Protein Ag2263
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5510, 66385
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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