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Invitrogen™ PPP1R8 Polyclonal Antibody
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Catalog No. PIPA541757
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100 μL
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Catalog No. Quantity
PIPA541757 100 μL
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Catalog No. PIPA541757 Supplier Invitrogen™ Supplier No. PA541757
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Description

Rabbit Polyclonal Antibody

Peptide sequence: PNLAPDVDLT PVVPSAVNMN PAPNPAVYNP EAVNEPKKKK YAKEAWPGKK Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 91%.

This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PPP1R8
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene PPP1R8
Gene Accession No. Q12972
Gene Alias 6330548N22Rik; activator of RNA decay; ARD1; ARD-1; AU044684; LOC100722083; NIPP1; NIPP-1; NIPP-1, nuclear inhibitor of protein phosphatase-1; Nuclear inhibitor of protein phosphatase 1; nuclear inhibitor of protein phosphatase-1 alpha; nuclear inhibitor of protein phosphatase-1 beta; nuclear subunit of PP-1; Ppp1r8; PRO2047; protein phosphatase 1 regulatory inhibitor subunit 8; protein phosphatase 1 regulatory subunit 8; protein phosphatase 1, regulatory (inhibitor) subunit 8; protein phosphatase 1, regulatory inhibitor subunit 8; protein phosphatase 1, regulatory subunit 8; RNase E
Gene Symbols PPP1R8
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human PPP1R8.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5511
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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