Invitrogen™ PPP1R8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA586723

Catalog No. PIPA586723

Description

Purity is > 95% by SDS-PAGE.

This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.

Specifications

• Antigen: PPP1R8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PPP1R8
• Gene Alias: 6330548N22Rik; activator of RNA decay; ARD1; ARD-1; AU044684; LOC100722083; NIPP1; NIPP-1; NIPP-1, nuclear inhibitor of protein phosphatase-1; Nuclear inhibitor of protein phosphatase 1; nuclear inhibitor of protein phosphatase-1 alpha; nuclear inhibitor of protein phosphatase-1 beta; nuclear subunit of PP-1; Ppp1r8; PRO2047; protein phosphatase 1 regulatory inhibitor subunit 8; protein phosphatase 1 regulatory subunit 8; protein phosphatase 1, regulatory (inhibitor) subunit 8; protein phosphatase 1, regulatory inhibitor subunit 8; protein phosphatase 1, regulatory subunit 8; RNase E
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100336, 313030, 5511
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q12972, Q8R3G1
• Gene Symbols: PPP1R8
• Immunogen: Synthetic peptide, corresponding to amino acids 237-282 of Human NIPP1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG