PPP2R1A Monoclonal Antibody (J.613.4), Invitrogen™

Rabbit Monoclonal Antibody

Supplier:  Thermo Scientific MA514952

Catalog No. PIMA514952

Description

It is not recommended to aliquot this antibody. This antibody is not cross-reactive with other PP2A subunits.

The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Upon interaction with GNA12 promotes dephosphorylation of microtubule associated protein TAU/MAPT. Required for proper chromosome segregation and for centromeric localization of SGO1 in mitosis.

Specifications

• Antigen: PPP2R1A
• Classification: Monoclonal
• Concentration: 11 μg/mL
• Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
• Gene Accession No.: P30153, Q76MZ3
• Gene Symbols: PPP2R1A
• Immunogen: Synthetic peptide corresponding to the sequence of human PP2A A Subunit protein
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Non-human Primate, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Clone: J.613.4
• Conjugate: Unconjugated
• Gene: PPP2R1A
• Gene Alias: 29B; 6330556D22Rik; 65 kDa regulatory subunit of protein phosphatase; A/PR65; alpha isoform of regulatory subunit A, protein phosphatase 2; CG13383; CG17291; CG17291-PA; CG17291-PB; CG17291-PC; CG17291-PD; CG17291-PE; CG33297; Dmel\CG17291; Dmel_CG17291; dPP2A A; DPR65; Medium tumor antigen-associated 61 kDa protein; MGC786; MRD36; PP2A; PP2A 29B; PP2A 65kD subunit A; PP2A A; PP2A subunit A isoform PR65-alpha; PP2A subunit A isoform R1-alpha; PP2A[A]; Pp2A29B; PP2A-29B; Pp2A-29B-PA; Pp2A-29B-PB; Pp2A-29B-PC; Pp2A-29B-PD; Pp2A-29B-PE; PP2A-A; PP2AAALPHA; PP2A-Aalpha; PP2Ac; PP2CA; PP2Calpha; Ppp2r1a; PR65; PR65A; protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform; protein phosphatase 2 (formerly 2A), regulatory subunit A , alpha isoform; protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform; protein phosphatase 2 regulatory subunit A, alpha; protein phosphatase 2 scaffold subunit Aalpha; protein phosphatase 2, regulatory subunit A, alpha; protein phosphatase 2A; protein phosphatase 2A at 29B; protein phosphatase PP2A; Protein phosphatase PP2A regulatory subunit A; protein phosphate 2A; regulatory subunit A of type 2A protein phosphatase; RP-C; serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, alpha isoform; serine/threonine protein phosphatase A subunit type 2A; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform; Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit; testicular secretory protein Li 1; Unknown (protein for MGC:128399)
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 117281, 51792, 5518
• Content And Storage: -20°C
• Form: Liquid