Invitrogen™ PPP2R1A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA527643

Catalog No. PIPA527643

Description

Recommended positive controls: HeLa, NIH-3T3, JC, BCL-1. Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (88%), Xenopus laevis (95%), Pig (100%), Rhesus Monkey (100%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Upon interaction with GNA12 promotes dephosphorylation of microtubule associated protein TAU/MAPT. Required for proper chromosome segregation and for centromeric localization of SGO1 in mitosis.

Specifications

• Antigen: PPP2R1A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PPP2R1A
• Gene Alias: 29B; 6330556D22Rik; 65 kDa regulatory subunit of protein phosphatase; A/PR65; alpha isoform of regulatory subunit A, protein phosphatase 2; CG13383; CG17291; CG17291-PA; CG17291-PB; CG17291-PC; CG17291-PD; CG17291-PE; CG33297; Dmel\CG17291; Dmel_CG17291; dPP2A A; DPR65; Medium tumor antigen-associated 61 kDa protein; MGC786; MRD36; PP2A; PP2A 29B; PP2A 65kD subunit A; PP2A A; PP2A subunit A isoform PR65-alpha; PP2A subunit A isoform R1-alpha; PP2A[A]; Pp2A29B; PP2A-29B; Pp2A-29B-PA; Pp2A-29B-PB; Pp2A-29B-PC; Pp2A-29B-PD; Pp2A-29B-PE; PP2A-A; PP2AAALPHA; PP2A-Aalpha; PP2Ac; PP2CA; PP2Calpha; Ppp2r1a; PR65; PR65A; protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform; protein phosphatase 2 (formerly 2A), regulatory subunit A , alpha isoform; protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform; protein phosphatase 2 regulatory subunit A, alpha; protein phosphatase 2 scaffold subunit Aalpha; protein phosphatase 2, regulatory subunit A, alpha; protein phosphatase 2A; protein phosphatase 2A at 29B; protein phosphatase PP2A; Protein phosphatase PP2A regulatory subunit A; protein phosphate 2A; regulatory subunit A of type 2A protein phosphatase; RP-C; serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, alpha isoform; serine/threonine protein phosphatase A subunit type 2A; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform; Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit; testicular secretory protein Li 1; Unknown (protein for MGC:128399)
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 117281, 51792, 5518
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 0.12 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: P30153, Q76MZ3
• Gene Symbols: PPP2R1A
• Immunogen: Recombinant fragment corresponding to a region within amino acids 308 and 589 of Human PPP2R1A.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov