PPP2R1B Mouse anti-Human, Clone: OTI8B6, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF811413

Catalog No. 50-167-0636

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4), is a putative member of a novel PP family. The PP2A family comprises subfamily members PP2A alpha and PP2A beta. The PP2A catalytic subunit associates with a variety of regulatory subunits. Regulatory subunits include PP2A-A alpha and -A beta, PP2A-B alpha and -B beta, PP2A-C alpha and -C beta, and PP2A-B56 alpha and -B56 beta.

Specifications

• Antigen: PPP2R1B
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: PPP2R1B
• Gene Alias: PP2A-Abeta, PR65B
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5519
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI8B6
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P30154
• Gene Symbols: PPP2R1B
• Immunogen: Human recombit protein fragment corresponding to amino acids 19-601 of human PPP2R1B produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1