PPP2R3A Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA550734
The antibody detects endogenous levels of total PPP2R3A protein.Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B ft./PR61, and B ft. ft./PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B ft. ft. family. The B ft. ft. family has been further divided into subfamilies. The product of this gene belongs to the alpha subfamily of regulatory subunit B ft. ft.. Alternative splicing results in multiple transcript variants encoding different isoforms.
|Synthetic peptide corresponding to a region derived from internal residues of human protein phosphatase 2, regulatory subunit B′′, alpha|
|Antigen affinity chromatography|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 50% glycerol and 0.05% sodium azide; pH 7.3|
|PR72, PR130, PPP2R3|
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