Invitrogen™ PPP2R3A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA530127

Catalog No. PIPA530127

Description

Recommended positive controls: NT2D1, U87-MG, MCF-7. Predicted reactivity: Human (99%), Mouse (90%), Rat (90%), Rhesus Monkey (97%), Bovine (92%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B'/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holoenzyme. The product of this gene belongs to the B' family. The B' family has been further divided into subfamilies. The product of this gene belongs to the alpha subfamily of regulatory subunit B'. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specifications

• Antigen: PPP2R3A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PPP2R3A
• Gene Alias: 3222402P14Rik; A730042E07; DNA for thyroid hormone receptor binding site (258bp); PP2A subunit B isoform PR72/PR130; PP2A subunit B isoform R3 isoform; PP2A subunit B isoforms B72/B130; PP2A subunit B isoforms B''-PR72/PR130; PP2A, subunit B, R3 isoform; PPP2R3; PPP2R3A; PR130; PR72; protein phosphatase 2 (formerly 2A), regulatory subunit B'' (PR 72), alpha isoform and (PR 130), beta isoform; protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha; protein phosphatase 2 regulatory subunit B'', alpha; protein phosphatase 2 regulatory subunit B''alpha; protein phosphatase 2, regulatory subunit B'', alpha; serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B; Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha; Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha-like protein
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5523
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q06190
• Gene Symbols: PPP2R3A
• Immunogen: Recombinant protein fragment corresponding to a region within amino acids 921 and 1129 of Human PPP2R3A.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov