Invitrogen™ PPP2R3B Monoclonal Antibody (2E12)

Catalog No.	Quantity
PIMA524568	100 μg

Catalog No. PIMA524568 Supplier Invitrogen™ Supplier No. MA524568

Description

Mouse Monoclonal Antibody

Peptide Sequence: MIDRIFSGAV TRGRKVQKEG KISYADFVWF LISEEDKKTP TSIEYWFRCM DLDGDGALSM FELEYFYEEQ CRRLDSMAIE ALPFQDCLCQ MLDLVKPRTE GKITLQDLKR CKLANVFFDT FFNIEKYLDH EQKEQISLLR DGDSGGPELS DWEKYAAEEY DILVAEETAG EPWEDGFEAE LSPVEQKLSA LRSPLAQRPF FEAPSPLGAV DLYEYACGDE DLEPL.

Protein phosphatase 2 is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B' '/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' ' family. The B' ' family has been further divided into subfamilies. The product of this gene belongs to the beta subfamily of regulatory subunit B' '. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specifications

• Antigen: PPP2R3B
• Applications: ELISA, Immunoprecipitation, Western Blot, Immunocytochemistry
• Classification: Monoclonal
• Clone: 2E12
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with no preservative; pH 7.4
• Gene: PPP2R3B
• Gene Accession No.: Q9Y5P8
• Gene Alias: NYREN8; NY-REN-8; NY-REN-8 antigen; PP2A subunit B isoform PR48; PP2A, subunit B, PR48 isoform; PPP2R3B; PPP2R3L; PPP2R3LY; PR48; protein phosphatase 2 (formerly 2A), regulatory subunit B' ', beta; protein phosphatase 2 regulatory subunit B' ', beta; protein phosphatase 2 regulatory subunit B' 'beta; protein phosphatase 2, regulatory subunit B' ', beta; Protein phosphatase 2A 48 kDa regulatory subunit; serine/threonine protein phosphatase 2A, 48kDa regulatory subunit B; serine/threonine-protein phosphatase 2A regulatory subunit B' ' subunit beta
• Gene Symbols: PPP2R3B
• Host Species: Mouse
• Immunogen: PPP2R3B (AAH11180, 1 a.a. ~ 225 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Purification Method: Protein A
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 28227
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2b κ