Invitrogen™ PPP2R4 Polyclonal Antibody

Catalog No.	Quantity
PIPA519136	100 μg

Catalog No. PIPA519136 Supplier Invitrogen™ Supplier No. PA519136

Description

Goat Polyclonal Antibody

This antibody is predicted to react with bovine and canine based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specifications

• Antigen: PPP2R4
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene: PTPA
• Gene Accession No.: P58389, Q15257
• Gene Alias: 2610042B21Rik; C77440; MGC2184; N28142; OTTHUMP00000022333; phosphotyrosyl phosphatase activator; PP2A; PP2A phosphatase activator; PP2A subunit B' isoform PR53; PP2A, subunit B', PR53 isoform; Ppp2r4; PR53; protein phosphatase 2 phosphatase activator; protein phosphatase 2 regulatory subunit 4; protein phosphatase 2A activator, regulatory subunit 4; protein phosphatase 2A activator, regulatory subunit B; protein phosphatase 2A regulatory subunit 4; protein phosphatase 2A, regulatory subunit B (PR 53); protein phosphatase 2A, regulatory subunit B' (PR 53); PTPA; Serine/threonine-protein phosphatase 2A activator; serine/threonine-protein phosphatase 2A regulatory subunit 4; Serine/threonine-protein phosphatase 2A regulatory subunit B'
• Gene Symbols: PTPA
• Host Species: Goat
• Immunogen: Synthetic peptide sequence (GSLLPIHPVTSG) corresponding to the C-terminus amino acids of PPP2R4 (aa 347-358).
• Purification Method: Ammonium sulfate precipitation
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 110854, 362102, 5524
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov