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Invitrogen™ PPP2R4 Polyclonal Antibody
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Catalog No. PIPA529755
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100 μL
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PIPA529755 100 μL
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Catalog No. PIPA529755 Supplier Invitrogen™ Supplier No. PA529755
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: A549, HeLa, HepG2, HCT116. Predicted reactivity: Mouse (96%), Rat (95%), Rabbit (94%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PPP2R4
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.74 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene PTPA
Gene Accession No. Q15257
Gene Alias 2610042B21Rik; C77440; MGC2184; N28142; OTTHUMP00000022333; phosphotyrosyl phosphatase activator; PP2A; PP2A phosphatase activator; PP2A subunit B' isoform PR53; PP2A, subunit B', PR53 isoform; Ppp2r4; PR53; protein phosphatase 2 phosphatase activator; protein phosphatase 2 regulatory subunit 4; protein phosphatase 2A activator, regulatory subunit 4; protein phosphatase 2A activator, regulatory subunit B; protein phosphatase 2A regulatory subunit 4; protein phosphatase 2A, regulatory subunit B (PR 53); protein phosphatase 2A, regulatory subunit B' (PR 53); PTPA; Serine/threonine-protein phosphatase 2A activator; serine/threonine-protein phosphatase 2A regulatory subunit 4; Serine/threonine-protein phosphatase 2A regulatory subunit B'
Gene Symbols PTPA
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human PPP2R4. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5524
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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