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Invitrogen™ PPP3CC Polyclonal Antibody
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Catalog No. PIPA582830
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100 μL
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PIPA582830 100 μL
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Catalog No. PIPA582830 Supplier Invitrogen™ Supplier No. PA582830
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: RGFSLQHKIR SFEEARGLDR INERMPPRKD SIHAGGPMKS VTSAHSHAAH RSDQGKKAHS Highest antigen sequence indentity to the following orthologs: Rat - 58%, Mouse - 59%.

Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. At least 3 genes, calcineurin A-alpha, calcineurin A-beta, and calcineurin A-gamma (CALNA3), have been cloned for the catalytic subunit. These genes have been identified in humans, mice, and rats, and are highly conserved between species (90 to 95% amino acid identity).
TRUSTED_SUSTAINABILITY

Specifications

Antigen PPP3CC
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PPP3CC
Gene Accession No. P48454
Gene Alias Calcineurin A gamma; Calcineurin, testis-specific catalytic subunit; calmodulin-dependent calcineurin A subunit gamma isoform; CALNA3; Calnc; CAM-PRP catalytic subunit; CNA3; PP2BA gamma; PP2Bgamma; PPP3CC; protein phosphatase 2B, catalytic subunit, gamma isoform; protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform; protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma); protein phosphatase 3 catalytic subunit gamma; protein phosphatase 3, catalytic subunit, gamma isoform; protein phosphatase 3, catalytic subunit, gamma isozyme; serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform
Gene Symbols PPP3CC
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PPP3CC. Recombinant protein control fragment (Product #RP-93771).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5533
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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