Invitrogen™ PPP4C Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA530128

Catalog No. PIPA530128

Description

Recommended positive controls: HepG2, NIH-3T3, JC, BCL-1. Predicted reactivity: Mouse (100%), Rat (99%), Xenopus laevis (99%), Rabbit (100%), Rhesus Monkey (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.

Specifications

• Antigen: PPP4C
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PPP4C
• Gene Alias: 1110002D08Rik; AU016079; P PPX; pp4; PP4C; PPH3; Ppp4; PPP4C; PPX; PP-X; protein phosphatase 4 (formerly X), catalytic subunit; protein phosphatase 4 catalytic subunit; protein phosphatase 4, catalytic subunit; protein phosphatase X; protein phosphatase X, catalytic subunit; serine/threonine-protein phosphatase 4 catalytic subunit
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5531, 56420
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ChIP Assay, Western Blot, Immunocytochemistry
• Concentration: 0.29 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P60510, P97470
• Gene Symbols: PPP4C
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 275 of Human PPP4C.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG