Tocris Bioscience™ PPTN hydrochloride

Description

High affinity and selective P2Y14 antagonist

PPTN hydrochloride is a high affinity and selective P2Y14 antagonist (KB = 434 pM), which exhibits >10,000-fold selectivity for P2Y14 over other P2Y receptors. PPTN inhibits UDP-glucose and MRS 2690 -induced porcine pancreatic artery contraction ex vivo, and also blocks UDP-glucose-induced chemotaxis of HL-60 leukemia cells in vitro.

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Specifications

• Chemical Name or Material: 4-[4-(4-Piperidinyl)phenyl]-7-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxylic acid hydrochloride
• CAS: 1992047-65-0
• Quantity: 10 mg
• Target: P2Y Receptor Antagonists
• Molecular Formula: C₂₉H₂₄F₃NO₂.HCl
• Formula Weight: 511.96
• Purity: >98%