Invitrogen™ PRDM12 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA599266

Catalog No. PIPA599266

Description

Antibody detects endogenous levels of total PRDM12.

This gene encodes a transcriptional regulator of sensory neuronal specification that plays a critical role in pain perception. The encoded protein contains an N-terminal PRDI-BF1 and RIZ homology (PR) domain, a SET domain, and three C-terminal C2H2 zinc finger DNA-binding domains. Naturally occurring mutations in this gene are associated with congenital insensitivity to pain (CIP), and hereditary sensory and autonomic neuropathies (HSAN's) affecting peripheral sensory and autonomic neurons. Deregulation of this gene is associated with solid cancers and hematological malignancies including chronic myeloid leukemia.

Specifications

• Antigen: PRDM12
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PRDM12
• Gene Alias: Gm998; HSAN8; PFM9; PR domain 12; PR domain containing 12; PR domain zinc finger protein 12; PR domain-containing protein 12; PRDM12; PR-domain containing protein 12; PR-domain zinc finger protein 12; RP11-57C19.7
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 381359, 59335
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: A2AJ77, Q9H4Q4
• Gene Symbols: PRDM12
• Immunogen: A synthesized peptide derived from human PRDM12(Accession Q9H4Q4), corresponding to amino acid residues L198-C248.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG