Invitrogen™ PRDX2 Monoclonal Antibody (7F5)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA542393

Catalog No. PIMA542393

Description

Positive Control: PC-3M, MCF-7. Subcellular Location: Cytoplasm.

Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, particularly amino-terminal region containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20 - 30 kilodalton in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distribution including peroxisome, mitochondria and cytosol.

Specifications

• Antigen: PRDX2
• Classification: Monoclonal
• Concentration: 2 mg/mL
• Formulation: PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P32119
• Gene Symbols: PRDX2
• Immunogen: Recombinant full length protein.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Western Blot
• Clone: 7F5
• Conjugate: Unconjugated
• Gene: PRDX2
• Gene Alias: AL022839; Band-8; Calpromotin; epididymis secretory sperm binding protein Li 2a; HEL-S-2a; HGNC:9353; MGC4104; Natural killer cell-enhancing factor B; NkefB; NKEF-B; peroxiredoxin 2; peroxiredoxin-2; Prdx2; protector protein; PRP; Prx II-1; PRX2; PRXII; PTX1; Tdpx1; TDX1; thiol specific antioxidant protein; thiol-specific antioxidant 1; thiol-specific antioxidant protein; thioredoxin dependent peroxide reductase 1; thioredoxin peroxidase 1; thioredoxin reductase; thioredoxin-dependent peroxide reductase 1; Torin; TPx; TPX1; TPx-B; TR; Trx dependent peroxide reductase 1; TSA
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 7001
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov