Invitrogen™ PRDX3 Recombinant Rabbit Monoclonal Antibody (4K7D1)

PRDX3 Recombinant Rabbit Monoclonal Antibody (ARC0747)

Supplier:  Invitrogen™ MA535357

Catalog No. PIMA535357

Description

PRDX3 Recombinant Monoclonal Antibody for Western Blot

Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20-30 kilodalton in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distribution including peroxisome, mitochondria and cytosol.

Specifications

• Antigen: PRDX3
• Classification: Recombinant Monoclonal
• Concentration: 0.25 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P20108, P30048
• Gene Symbols: PRDX3
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 157-256 of human Peroxiredoxin 3 (PRDX3) (PRDX3) (P30048).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 4K7D1
• Conjugate: Unconjugated
• Gene: PRDX3
• Gene Alias: antioxidant protein; antioxidant protein 1; anti-oxidant protein 1; Aop1; AOP-1; AW822249; D0Tohi1; Ef2l; HBC189; Mer5; mitochondrial thioredoxin dependent peroxide reductase; mitochondrial Trx dependent peroxide reductase; perioredoxin-3; peroxiredoxin 3; peroxiredoxin III; Peroxiredoxin-3; Prdx3; PRO1748; Protein MER5; Protein MER5 homolog; Prx; Prx 3; PRx III; Prx3; PRX-3; Prx-III; SP22; SP-22; TDXM; thioredoxin-dependent peroxide reductase, mitochondrial
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10935, 11757
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid