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Invitrogen™ PRDX3 Polyclonal Antibody
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Catalog No. PIPA5116556
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100 μL
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PIPA5116556 100 μL
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Catalog No. PIPA5116556 Supplier Invitrogen™ Supplier No. PA5116556
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Description

Rabbit Polyclonal Antibody

Positive Samples: U-87MG, HeLa, LO2, A-549, Mouse kidney Immunogen sequence: PAVTQHAPYF KGTAVVNGEF KDLSLDDFKG KYLVLFFYPL DFTFVCPTEI VAFSDKANEF HDVNCEVVAV SVDSHFSHLA WINTPRKNGG LGHMNIALLS DLTKQISRDY GVLLEGSGLA LRGLFIIDPN GVIKHLSVND LPVGRSVEET LRLVKAFQYV ETHGEVCPAN WTPDSPTIKP SPAASKEYFQ KVNQ.

Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20-30 kilodalton in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distribution including peroxisome, mitochondria and cytosol.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PRDX3
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.01 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene PRDX3
Gene Accession No. P20108, P30048, Q9Z0V6
Gene Alias antioxidant protein; antioxidant protein 1; anti-oxidant protein 1; Aop1; AOP-1; AW822249; D0Tohi1; Ef2l; HBC189; Mer5; mitochondrial thioredoxin dependent peroxide reductase; mitochondrial Trx dependent peroxide reductase; perioredoxin-3; peroxiredoxin 3; peroxiredoxin III; Peroxiredoxin-3; Prdx3; PRO1748; Protein MER5; Protein MER5 homolog; Prx; Prx 3; PRx III; Prx3; PRX-3; Prx-III; SP22; SP-22; TDXM; thioredoxin-dependent peroxide reductase, mitochondrial
Gene Symbols PRDX3
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 63-256 of human Peroxiredoxin 3 (Peroxiredoxin 3 (PRDX3)) (NP_0067841).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10935, 11757, 64371
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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