Invitrogen™ PRDX4 Recombinant Rabbit Monoclonal Antibody (9E7V0)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA535759

Catalog No. PIMA535759

Description

Immunogen sequence: MEALPLLAAT TPDHGRHRRL LLLPLLLFLL PAGAVQGWET EERPRTREEE CHFYAGGQVY PGEASRVSVA DHSLHLSKAK ISKPAPYWEG TAVIDGEFKE.

Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20-30 kilodalton in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distribution including peroxisome, mitochondria and cytosol.

Specifications

• Antigen: PRDX4
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O08807, Q13162, Q9Z0V5
• Gene Symbols: PRDX4
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Peroxiredoxin 4 (PRDX4) (PRDX4) (Q13162).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 9E7V0
• Conjugate: Unconjugated
• Gene: PRDX4
• Gene Alias: Antioxidant enzyme AOE372; AOE372; AOE37-2; EC 1.11.1.15; epididymis secretory sperm binding protein Li 97n; HEL-S-97n; peroxiredoxin 4; peroxiredoxin IV; Peroxiredoxin-4; Prdx4; Prx 4; Prx IV; Prx4; PRX-4; prx-IV; Rno2CysPrx04; Thioredoxin dependent peroxide reductase A0372; thioredoxin peroxidase (antioxidant enzyme); thioredoxin peroxidase AO372; Thioredoxin-dependent peroxide reductase A0372; TRANK
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10549, 53381, 85274
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid