Invitrogen™ PRDX4 Recombinant Rabbit Monoclonal Antibody (SAIC-40A-24)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA547919

Catalog No. PIMA547919

Description

Specificity: Recognises human PRDX4.

Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20-30 kilodalton in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distribution including peroxisome, mitochondria and cytosol.

Specifications

• Antigen: PRDX4
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% ProClin 300
• Gene Accession No.: Q13162
• Gene Symbols: PRDX4
• Immunogen: Peptide QITLNDLPVGR, derived from the cell redox-regulator Peroxiredoxin-4, conjugated to KLH.
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG κ

• Applications: ELISA, Flow Cytometry, Western Blot, Immunocytochemistry, Mass Spectrometry
• Clone: SAIC-40A-24
• Conjugate: Unconjugated
• Gene: PRDX4
• Gene Alias: Antioxidant enzyme AOE372; AOE372; AOE37-2; EC 1.11.1.15; epididymis secretory sperm binding protein Li 97n; HEL-S-97n; peroxiredoxin 4; peroxiredoxin IV; Peroxiredoxin-4; Prdx4; Prx 4; Prx IV; Prx4; PRX-4; prx-IV; Rno2CysPrx04; Thioredoxin dependent peroxide reductase A0372; thioredoxin peroxidase (antioxidant enzyme); thioredoxin peroxidase AO372; Thioredoxin-dependent peroxide reductase A0372; TRANK
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 10549
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid