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Invitrogen™ PRDX4 Recombinant Rabbit Monoclonal Antibody (SAIC-40C-8)
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Catalog No. PIMA547920
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200 μg
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Catalog No. Quantity
PIMA547920 200 μg
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Catalog No. PIMA547920 Supplier Invitrogen™ Supplier No. MA547920
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Description

Rabbit Recombinant Monoclonal Antibody

Specificity: Recognises human PRDX4.

Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20-30 kilodalton in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distribution including peroxisome, mitochondria and cytosol.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PRDX4
Applications ELISA, Flow Cytometry, Western Blot, Immunocytochemistry, Mass Spectrometry
Classification Recombinant Monoclonal
Clone SAIC-40C-8
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% ProClin 300
Gene PRDX4
Gene Accession No. Q13162
Gene Alias Antioxidant enzyme AOE372; AOE372; AOE37-2; EC 1.11.1.15; epididymis secretory sperm binding protein Li 97n; HEL-S-97n; peroxiredoxin 4; peroxiredoxin IV; Peroxiredoxin-4; Prdx4; Prx 4; Prx IV; Prx4; PRX-4; prx-IV; Rno2CysPrx04; Thioredoxin dependent peroxide reductase A0372; thioredoxin peroxidase (antioxidant enzyme); thioredoxin peroxidase AO372; Thioredoxin-dependent peroxide reductase A0372; TRANK
Gene Symbols PRDX4
Host Species Rabbit
Immunogen Peptide LVQAFQYTDK derived from the cell redox-regulator Peroxiredoxin-4, conjugated to KLH.
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10549
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG κ
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