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Invitrogen™ PRDX5 Recombinant Rabbit Monoclonal Antibody (5E10D3)
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Catalog No. PIMA535424
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100 μL
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PIMA535424 100 μL
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Catalog No. PIMA535424 Supplier Invitrogen™ Supplier No. MA535424
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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: CSKTHLPGFV EQAEALKAKG VQVVACLSVN DAFVTGEWGR AHKAEGKVRL LADPTGAFGK ETDLLLDDSL VSIFGNRRLK RFSMVVQDGI VKALNVEPDG T.

Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20-30 kilodalton in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distribution including peroxisome, mitochondria and cytosol.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PRDX5
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 5E10D3
Concentration 0.6 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PRDX5
Gene Accession No. P30044, P99029, Q9R063
Gene Alias ACR1; Alu corepressor 1; Alu co-repressor 1; Antioxidant enzyme B166; AOEB166; AOPP; B166; epididymis secretory protein Li 55; HEL-S-55; Liver tissue 2D-page spot 2D-0014IV; liver tissue 2D-page spot 71B; peroxiredoxin 5; peroxiredoxin 6; peroxiredoxin V; Peroxiredoxin-5, mitochondrial; peroxisomal antioxidant enzyme; peroxisomal membrane protein 20; PLP; Pmp20; PRDX5; Prdx6; Prx5; PrxV; prx-V; SBBI10; Thioredoxin peroxidase PMP20; thioredoxin reductase; TPx type VI
Gene Symbols PRDX5
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Peroxiredoxin 5 (PRDX5) (PRDX5) (P30044).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 113898, 25824, 54683
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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