Invitrogen™ PRDX6 Polyclonal Antibody

Catalog No.	Quantity
PIPA582272	100 μL

Catalog No. PIPA582272 Supplier Invitrogen™ Supplier No. PA582272

Description

Rabbit Polyclonal Antibody

Immunogen sequence: GGLLLGDVAP NFEANTTVGR IRFHDFLGDS WGILFSHPRD FTPVCTTELG RAAKLAPEFA KRNVKLIALS IDSVEDHLAW SKDINAYNCE EPTEKLPFPI IDDRNRELAI LLGMLDPAEK DEKGMPVTAR VVFVFGPDKK LKLSILYPA Highest antigen sequence indentity to the following orthologs: Mouse - 92%, Rat - 93%.

Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20-30 kilodalton in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distribution including peroxisome, mitochondria and cytosol.

Specifications

• Antigen: PRDX6
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.05 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: PRDX6
• Gene Accession No.: P30041
• Gene Alias: 1-Cys; 1-Cys peroxiredoxin; 1-Cys PRX; 1-cysPrx; 24 kDa protein; 9430088D19Rik; AA690119; Acidic calcium-independent phospholipase A2; aiPLA2; Antioxidant protein 2; Aop2; Brp-12; CP-3; epididymis secretory sperm binding protein Li 128m; GPx; HEL-S-128m; KIAA0106; Liver 2D page spot 40; Ltw4; Ltw-4; Lvtw-4; MGC46173; MSP23; NKEFA; Non-selenium glutathione peroxidase; NSGPx; ORF06; p29; PAG; PAGA; PAGB; peroxiredoxin 6; peroxiredoxin-6; Prdx5; Prdx6; PRX; Prx6; Red blood cells page spot 12; thiol-specific antioxidant protein; Tsa
• Gene Symbols: PRDX6
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to Human PRDX6. Recombinant protein control fragment (Product #RP-89190).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 9588
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG