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  6. Prednisone, 98%, Thermo Scientific Chemicals

Prednisone, 98%, Thermo Scientific Chemicals

Catalog No. AC448950050
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Quantity:
5 g
Packaging:
Glass bottle

Description

Prednisone, 98%, CAS # 53-03-2, is a synthetic glucocorticoid with anti-inflammatory, immunomodulatory, antineoplastic, and adrenergic activities.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Prednisone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive activities

• It shows antineoplastic and adrenergic activities against hormone-sensitive cancer cells

• This compound binds to its receptors and enters the nucleus activating specific nuclear receptors, resulting in an altered gene expression and inhibiting proinflammatory cytokine production

Applications

• Prednisone can reduce circulating lymphocytes, promote cell differentiation, and stimulate apoptosis in sensitive tumor cell lines

• It is considered a prodrug that is converted by the liver into prednisolone which is the active steroid compound

• It is also used in some studies to investigate the effects of daily administration of MIDD0301, on the animal and organs weights and hematological profile

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 53-03-2
Molecular Formula C21H26O5
Molecular Weight (g/mol) 358.434
InChI Key XOFYZVNMUHMLCC-ZPOLXVRWSA-N
Synonym prednisone, deltasone, dehydrocortisone, decortin, meticorten, orasone, prednison, rectodelt, ultracorten, dacortin
PubChem CID 5865
ChEBI CHEBI:8382
IUPAC Name (8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
SMILES CC12CC(=O)C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C

Specifications

Assay Percent Range 98%
Packaging Glass bottle
Quantity 5 g
Formula Weight 358.43
Chemical Name or Material Prednisone

RUO – Research Use Only

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