Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. MA126321

Invitrogen™ Plasma Kallikrein Monoclonal Antibody (13G11)
GREENER_CHOICE

Catalog No. MA126321
Change view
Click to view available options
Quantity:
50 μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
MA126321 50 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. MA126321 Supplier Invitrogen™ Supplier No. MA126321
Add to Cart
Add to Cart

Description

Mouse Monoclonal Antibody

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Plasma prekallikrein is a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. It is synthesized in the liver and secreted into the blood as a single polypeptide chain. Plasma prekallikrein is converted to plasma kallikrein by factor XIIa by the cleavage of an internal Arg-Ile bond. Plasma kallikrein therefore is composed of a heavy chain and a light chain held together by a disulphide bond. The heavy chain originates from the amino-terminal end of the zymogen and contains 4 tandem repeats of 90 or 91 amino acids. Each repeat harbors a novel structure called the apple domain. The heavy chain is required for the surface-dependent pro-coagulant activity of plasma kallikrein. The light chain contains the active site or catalytic domain of the enzyme and is homologous to the trypsin family of serine proteases. Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Plasma Kallikrein
Applications ELISA, Western Blot
Classification Monoclonal
Clone 13G11
Concentration 1.5 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene Klkb1
Gene Accession No. P03952
Gene Alias antigen, prostate specific; APS; EC 3.4.21.34; Fletcher factor; Kal3; Kal-3; kallikrein; kallikrein 3, plasma; kallikrein B plasma; kallikrein B, plasma (Fletcher factor) 1; kallikrein B, plasma 1; kallikrein B1; Kalp1; KALP15; kininogenin; Klk3; KLKB1; Pk; PKK; PKKD; plasma kallikrein; Plasma kallikrein heavy chain; Plasma kallikrein light chain; Plasma prekallikrein; PPK; prekallikrein; PSA
Gene Symbols Klkb1
Host Species Mouse
Immunogen Purified human prekallikrein.
Purification Method Protein G
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3818
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
Show More Show Less

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.