Invitrogen™ PRELP Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120649

Catalog No. PIPA5120649

Description

Positive test controls include: Mouse lung, Rat heart. Immunogen sequence: LDLQHNRLSD GVFKPDTFHG LKNLMQLNLA HNILRKMPPR VPTAIHQLYL DSNKIETIPN GYFKSFPNLA FIRLNYNKLT DRGLPKNSFN ISNLLVLHLS HNRISSVPAI NNRLEHLYLN NNSIEKINGT QICPNDLVAF HDFSSDLENV PHLRYLRLDG N.

PRELP is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage.

Specifications

• Antigen: PRELP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PRELP
• Gene Alias: 55 kDa leucine-rich repeat protein of articular cartilage; 7330409J17Rik; MST161; MSTP161; PRELP; Prolargin; prolargin proteoglycan; proline and arginine rich end leucine rich repeat protein; proline arginine-rich end leucine-rich repeat; proline/arginine-rich end leucine-rich repeat protein; proline-arginine-rich end leucine-rich repeat protein; SLRR2A
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 116847, 84400
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 3.14 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q9EQP5, Q9JK53
• Gene Symbols: PRELP
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 200-360 of human PRELP (NP_002716.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG