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Invitrogen™ PREP Polyclonal Antibody
Goat Polyclonal Antibody
Supplier: Invitrogen™ PA547611
Description
In direct ELISAs and Western blots, approximately 25% cross-reactivity with recombinant mouse PREP is observed. Reconstitute at 0.2 mg/mL in sterile PBS.
p33cdk2 associates with cyclin A in human cells. Kinase activity associated with cyclin A-cdc2 is found only in G2-phase. Cdk2 also complexes with cyclins E, D1, and D3. Cyclin E-cdk2 kinase is active in the G1- and S-phases of the cell cycle and is important (as does cyclin A-cdk2) for the progression from G1-to S-phase. The levels of cyclin A-cdk2 is maximal at the G1/S transition and both cdk2 and cyclin A are found associated with DNA in the initiation complex during replication. Rb protein acts as substrate for cdk2-cyclin E and/or cdk2-cyclin A in vivo. Cdk2 is activated and specifically localized to the nucleus during late G1-, S-, and G2-phase.
Specifications
PREP | |
Polyclonal | |
Unconjugated | |
PREP | |
AI047692; AI450383; D10Wsu136e; dJ355L5.1 (prolyl endopeptidase); EC 3.4.21.26; MGC16060; PE; PE {ECO:0000250; PEP; Pop; post-proline cleaving enzyme; post-proline cleaving enzyme {ECO:0000250; Prep; prep {ECO:0000312; Prolyl endopeptidase; prolyl endopeptidase {ECO:0000250; prolyl oligopeptidase; RGD:620841}; rPop; UniProtKB:P23687} | |
Goat | |
Antigen affinity chromatography | |
RUO | |
5550 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Immunoprecipitation, Western Blot | |
0.2 mg/mL | |
PBS with 5% trehalose and No Preservative | |
P48147 | |
PREP | |
Sf 21-derived recombinant human PREP Leu2-Pro710. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG |
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