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Invitrogen™ PREP Polyclonal Antibody
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Catalog No. PIPA556725
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100 μL
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PIPA556725 100 μL
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Catalog No. PIPA556725 Supplier Invitrogen™ Supplier No. PA556725
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LSIREGCDPV NRLWYCDLQQ ESSGIAGILK WVKLIDNFEG EYDYVTNEGT VFTFKTNRQS PNYRVINIDF RDPEESKWKV LVPEHEKD Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 86%.

p33cdk2 associates with cyclin A in human cells. Kinase activity associated with cyclin A-cdc2 is found only in G2-phase. Cdk2 also complexes with cyclins E, D1, and D3. Cyclin E-cdk2 kinase is active in the G1- and S-phases of the cell cycle and is important (as does cyclin A-cdk2) for the progression from G1-to S-phase. The levels of cyclin A-cdk2 is maximal at the G1/S transition and both cdk2 and cyclin A are found associated with DNA in the initiation complex during replication. Rb protein acts as substrate for cdk2-cyclin E and/or cdk2-cyclin A in vivo. Cdk2 is activated and specifically localized to the nucleus during late G1-, S-, and G2-phase.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PREP
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PREP
Gene Accession No. P48147
Gene Alias AI047692; AI450383; D10Wsu136e; dJ355L5.1 (prolyl endopeptidase); EC 3.4.21.26; MGC16060; PE; PE {ECO:0000250; PEP; Pop; post-proline cleaving enzyme; post-proline cleaving enzyme {ECO:0000250; Prep; prep {ECO:0000312; Prolyl endopeptidase; prolyl endopeptidase {ECO:0000250; prolyl oligopeptidase; RGD:620841}; rPop; UniProtKB:P23687}
Gene Symbols PREP
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PREP. Recombinant protein control fragment (Product #RP-94645).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5550
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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