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Tocris Bioscience™ preQ1-alkyne
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Catalog No. 780610
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78-061-0 10 mg
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Description

preQ1 with alkyne handle for click chemistry

preQ1-alkyne is a modified analog of the natural substrate prequeosine1 (preQ1). It contains alkyne handle that enables users to attach additional groups to preQ1 via Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry. It can be used to generate photoactivatable probes that can control CRISPR gene editing via the RNA-TAG method.

Other RNA-TAG toolbox compounds include preQ1-biotin ( Cat. No. 7804 )

Plasmids for expression of the E.coli TGT enzyme ( #138201 ) and for cloning an RNA of interest into a vector containing the recognition motif at the 3' end ( #138209 ) are available from Addgene.

Specifications

Chemical Name or Material N-[6-[[(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]amino]hexyl]-3-(2-propyn-1-yloxy)propanamide
CAS 2771096-76-3
Quantity 10 mg
Target CRISPR Reagents
Molecular Formula C19H28N6O3
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