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Invitrogen™ PREX2 Polyclonal Antibody
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Catalog No. PIPA553288
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100 μL
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PIPA553288 100 μL
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Catalog No. PIPA553288 Supplier Invitrogen™ Supplier No. PA553288
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GLGFQIRGFG PSVVHAVGRG TVAAAAGLHP GQCIIKVNGI NVSKETHASV IAHVTACRKY RRPTKQDSIQ WVYNSIESAQ EDLQKSHSKP PGDEAGDAFD CKVEEVIDKF NTMAIIDGKK EHVSLTVDNV HLEYGVVYEY DSTAGIKCNV Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 93%.

Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PREX2
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PREX2
Gene Accession No. Q70Z35
Gene Alias 6230420N16Rik; AI316880; AI553603; C030045D06Rik; D430013K02; DEP domain containing 2; DEP domain-containing protein 2; DEP.2; Depdc2; phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein; phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2; phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2; PPP1R129; Prex2; P-Rex2; protein phosphatase 1, regulatory subunit 129; ptdIns(3,4,5)-dependent Rac exchanger 2; si:ch211-278g15.1
Gene Symbols PREX2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PREX2. Recombinant protein control fragment (Product #RP-90632).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 80243
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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