PRKAA2 Mouse anti-Human, Clone:5B4G1, Abnova™

Catalog No.	Quantity
89-333-930	100 μg

Catalog No. 89-333-930 Supplier Abnova Corporation Supplier No. MAB17501

Description

Mouse monoclonal antibody raised against recombinant human PRKAA2.

The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq]

Specifications

• Antigen: PRKAA2
• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: 5B4G1
• Conjugate: Unconjugated
• Description: protein kinase, AMP-activated, alpha 2 catalytic subunit
• Dilution: ELISA (1:10000)
  Western Blot (1:500-1:2000)
  Immunocytochemistry
  Flow Cytometry
  Immunohistochemistry (1:200-1:1000)
  The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.05% sodium azide)
• Gene: PRKAA2
• Gene Alias: AMPK, AMPK2, PRKAA
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to amino acid 453-552 of human PRKAA2 from E. coli.
• Quantity: 100 μg
• Gene ID (Entrez): 5563
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1