PRKAB2 Mouse anti-Human, Clone:8F5B2, Abnova™

Catalog No.	Quantity
89-334-389	100 μg

Catalog No. 89-334-389 Supplier Abnova Corporation Supplier No. MAB17941

Description

Mouse monoclonal antibody raised against partial recombinant human PRKAB2.

The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. [provided by RefSeq]

Specifications

• Antigen: PRKAB2
• Applications: ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: 8F5B2
• Conjugate: Unconjugated
• Description: protein kinase, AMP-activated, beta 2 non-catalytic subunit
• Dilution: ELISA (1:10000)
  Flow Cytometry (1:200-1:400)
  Immunofluorescence (1:200-1:1000)
  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  Western Blot (1:100-1:500)
  The optimal working dilution should be determined by the end user
• Formulation: In PBS (0.05% sodium azide)
• Gene: PRKAB2
• Gene Alias: MGC61468
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to amino acids 1-120 of human PRKAB2.
• Quantity: 100 μg
• Gene ID (Entrez): 5565
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1