PRKAG3 Mouse anti-Human, Clone:2C7A7, Abnova™

Catalog No.	Quantity
89-334-350	100 μg

Catalog No. 89-334-350 Supplier Abnova Corporation Supplier No. MAB17902

Description

Mouse monoclonal antibody raised against partial recombinant human PRKAG3.

The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle. [provided by RefSeq]

Specifications

• Antigen: PRKAG3
• Applications: ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: 2C7A7
• Conjugate: Unconjugated
• Description: protein kinase, AMP-activated, gamma 3 non-catalytic subunit
• Dilution: ELISA (1:10000)
  Immunofluorescence (1:200-1:1000)
  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  Western Blot (1:100-1:500)
  The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.05% sodium azide)
• Gene: PRKAG3
• Gene Alias: AMPKG3
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to amino acids 9-151 of human PRKAG3.
• Quantity: 100 μg
• Gene ID (Entrez): 53632
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1