Invitrogen™ Human PRKCZ (PKC zeta) Recombinant Protein

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Recombinant, Full Length Assay Entry: Biochemical terbium phospho-specific activity, Biochemical phospho-specific activity (no antibody) System Compatibility: LanthaScreen™ Antibody, LanthaScreen™ Substrate, Z'-LYTE™, Omnia™ Bulk Substrate

The PKC family of serine/threonine kinases, including PRKCZ (PKC zeta), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent. PKC zeta plays a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function.

Specifications

• Accession Number: Q05513
• Concentration: See Label
• For Use With (Application): Kinase Assay
• Formulation: 20 mM HEPES with 0.05% Triton X-100, 250 mM NaCl, 2 mM EDTA, 2 mM EGTA, 50% glycerol, 5 mM DTT and no preservative; pH 7.5
• Gene ID (Entrez): 5590
• Molecular Weight (g/mol): 67.7 kDa
• Name: Human PRKCZ (PKC zeta)
• Quantity: 5 μg
• Gene Alias: 14 - 3 - 3 - zeta isoform; 14-3-3-zetaisoform; AI098070; aPKCzeta; atypical protein kinase C; C80388; kinase nPKC-zeta; KPCZ; nPKC-zeta; nPKC-zeta PRKCZ; PKC2; Pkcz; PKC-ZETA; Prkcz; protein kinase C zeta; protein kinase C zeta subspecies; protein kinase C zeta type; protein kinase C, zeta; r14-3-3; R74924; zetaPKC
• Common Name: PKC zeta
• KinaseFamily: PKC Kinase Family
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Sequence: Full length
• Content And Storage: -80°C, Avoid Freeze/Thaw Cycles
• Assay Entry: Biochemical terbium phospho-specific activity, Biochemical phospho-specific activity (no antibody)
• Kinase Group: Ser⁄Thr Kinases: AGC Group
• Shipping Condition: Dry Ice
• System Compatibility: LanthaScreen™ Antibody, LanthaScreen™ Substrate, Z'-LYTE™, Omnia™ Bulk Substrate
• Target Entry: PRKCZ
• Target Gene: protein kinase C, zeta
• Expression System: Insect cells
• Protein Family: Kinases & Inhibitors
• Protein Form: Recombinant, Full Length
• Form: Liquid
• Protein Subtype: Serine/Threonine Kinases
• Research Category: Signal Transduction