Invitrogen™ PRKD3 Polyclonal Antibody

Catalog No.	Quantity
PIPA5100915	100 μL

Catalog No. PIPA5100915

Supplier: Invitrogen™ PA5100915

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total PRKD3.

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members.

Specifications

• Antigen: PRKD3
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: Prkd3
• Gene Accession No.: O94806, Q8K1Y2
• Gene Alias: 4930557O20Rik; 5730497N19Rik; EPK2; nPKC-D1; nPKC-mu; nPKC-nu; PKCM; PKC-MU; Pkcnu; PKC-NU; PKD; PKD1; PKD3; PRKCM; Prkcn; PRKD1; Prkd3; Protein kinase C mu type; protein kinase C nu type; protein kinase C, mu; protein kinase C, nu; protein kinase D; protein kinase D1; protein kinase D3; protein kinase EPK2; Serine/threonine-protein kinase D1; serine/threonine-protein kinase D3
• Gene Symbols: Prkd3
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human PRKD3(Accession O94806), corresponding to amino acid residues A25-I75.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 23683, 313834, 75292
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov