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PRKD3 Mouse anti-Human, Clone: OTI4G6, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA526756

Catalog No. PIMA526756


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Description

Description

Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes including conventional (c) PKC isoforms ( alpha, betaI, betaII and gamma) and novel (n) PKC isoforms ( delta, epsilon, zeta, eta and theta). Patterns of expression for each PKC isoform differs among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of nPKC delta and epsilon are independent of Ca 2+. On the other hand, nPKC delta and epsilon, as well as all of the cPKC members, possess phorbol ester-binding activities and kinase activities.
Specifications

Specifications

PRKD3
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
O94806
EPK2, PKC-NU, PKD3, PRKCN, nPKC-NU, protein kinase C nu type, protein kinase C, nu, protein kinase EPK2, protein-serine/threonine kinase, serine/threonine-protein kinase D3
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
23683
Immunohistochemistry (Paraffin), Western Blot
OTI4G6
Unconjugated
PRKD3
Liquid
PRKD3
Human recombit protein fragment corresponding to amino acids 300-508 of PRKD3 produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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