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PRL3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 151861AP

Catalog No. 50-173-0047


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Description

Description

The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist. PRL-3 expression was found to be up-regulated in human liver carcinoma compared with normal liver. Its expression in colorectal cancers may contribute to the establishment of liver metastasis. In a different study, PRL-3 is found to be expressed in tumor metastasis and vasculature, regardless of the tumor source.
Specifications

Specifications

PRL3
0.13 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
O75365, Q9D658
PRL 3, PRL R, PRL3, PTP4A3
Rabbit
IgG
150 μL
-20°C
Primary
11156, 19245, 362930
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
PTP4A3
Liquid
Ptp4a3
PRL3 Fusion Protein Ag7249
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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