Invitrogen™ PRMT1 Monoclonal Antibody (GT10111)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA531503

Catalog No. PIMA531503

Description

Keep as concentrated solution. Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (100%), Bovine (100%). Positive Control: 293T, A431, HeLa, HepG2, Neuro2A, GL261, NIH-3T3, Raw264.7, C2C12. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

PRMT1 is a member of the protein arginine N-methyltransferase (PRMT) family. Arginine methylation is an irreversible post translational modification which has been implicated in RNA processing and trafficking, receptor-mediated signaling, and transcription. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These proteins include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Increased expression of PRMT1 may play a role in various types of cancer.

Specifications

• Antigen: PRMT1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: Q99873, Q9JIF0
• Gene Symbols: PRMT1
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PRMT1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: GT10111
• Conjugate: Unconjugated
• Gene: PRMT1
• Gene Alias: 6720434D09Rik; ANM1; arginine N-methyltransferase 1; AW214366; HCP1; heterogeneous nuclear ribonucleoprotein methyltransferase 1-like 2; heterogeneous nuclear ribonucleoproteins methyltransferase-like 2; histone-arginine N-methyltransferase PRMT1; HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 2; HMT1 hnRNP methyltransferase-like 2; HMT1 hnRNP methyltransferase-like 2 isoform 3; HMT2; Hrmt1l2; interferon receptor 1-bound protein 4; IR1B4; Mrmt1; PRMT1; protein arginine methyltransferase 1; protein arginine N-methyltransferase 1
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 15469, 3276
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid