Invitrogen™ PRMT2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA541711

Catalog No. PIPA541711

Description

Peptide sequence: ERAGCCGYIP ANHVGKHVDE YDPEDTWQDE EYFGSYGTLK LHLEMLADQP Sequence homology: Human: 100%; Rat: 79%.

Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. Acts as a coactivator (with NCOA2) of the androgen receptor (AR)-mediated transactivation. Acts as a coactivator (with estrogen) of estrogen receptor (ER)-mediated transactivation. Enhances PGR, PPARG, RARA-mediated transactivation. May inhibit NF-kappa-B transcription and promote apoptosis. Represses E2F1 transcriptional activity (in a RB1-dependent manner). May be involved in growth regulation. [UniProt].

Specifications

• Antigen: PRMT2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PRMT2
• Gene Alias: histone-arginine N-methyltransferase PRMT2; HMT1; HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 1; HMT1 hnRNP methyltransferase-like 1; Hrmt1l1; MGC111373; Prmt2; PRMT2 alpha; PRMT2 beta; PRMT2 gamma; protein arginine methyltransferase 2; protein arginine N-methyltransferase 2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3275
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ChIP Assay, Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: P55345
• Gene Symbols: PRMT2
• Immunogen: Synthetic peptide directed towards the N-terminal of human PRMT2 (aa 71-120).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov