Invitrogen™ PRMT4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA141103

Catalog No. 01-675-691

Description

Suggested positive control: Hela whole cell extract, HeLa cell lysate.

Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in DNA packaging, transcription regulation, signal transduction, mRNA stability, metabolism of nascent pre-RNA, and transcriptional activation. Tissue specificity: Overexpressed in prostate adenocarcinomas and high-grade prostatic intraepithelial neoplasia.

Specifications

• Antigen: PRMT4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Carm1
• Gene Alias: Carm1; coactivator associated arginine methyltransferase 1; coactivator-associated arginine methyltransferase 1; coactivator-associated arginine methyltransferase 1 variant 5; histone-arginine methyltransferase CARM1; PRMT4; protein arginine methyltransferase; protein arginine N-methyltransferase 4
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 10498
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.05% BSA and 0.05% sodium azide
• Gene Accession No.: Q86X55
• Gene Symbols: Carm1
• Immunogen: Synthetic peptides coorresponding to residues 45-69 and 595-608 of human PRMT4.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov