Invitrogen™ PRMT4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578913

Catalog No. PIPA578913

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human 293T whole cell, human Hela whole cell, human MCF-7 whole cell, human HepG2 whole cell, rat testis tissue, rat C6 whole cell.

Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in DNA packaging, transcription regulation, signal transduction, mRNA stability, metabolism of nascent pre-RNA, and transcriptional activation. Tissue specificity: Overexpressed in prostate adenocarcinomas and high-grade prostatic intraepithelial neoplasia.

Specifications

• Antigen: PRMT4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Carm1
• Gene Alias: Carm1; coactivator associated arginine methyltransferase 1; coactivator-associated arginine methyltransferase 1; coactivator-associated arginine methyltransferase 1 variant 5; histone-arginine methyltransferase CARM1; PRMT4; protein arginine methyltransferase; protein arginine N-methyltransferase 4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10498, 363026
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and no preservative
• Gene Accession No.: Q4AE70, Q86X55
• Gene Symbols: Carm1
• Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human PRMT4 (267-284aa HLAPFTDEQLYMEQFTKA).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Rat, Rat
• Product Type: Antibody
• Isotype: IgG