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Invitrogen™ PRMT5 Monoclonal Antibody (GT3610)
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Catalog No. PIMA531465
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100 μL
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Catalog No. Quantity
PIMA531465 100 μL
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Catalog No. PIMA531465 Supplier Invitrogen™ Supplier No. MA531465
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Description

Mouse Monoclonal Antibody

Keep as concentrated solution. Predicted reactivity: Mouse (98%), Rat (98%), Zebrafish (85%), Japanese Medaka (86%), Xenopus laevis (91%), Pig (100%), Rhesus Monkey (100%), Chimpanzee (99%), Bovine (98%). Positive Control: Jurkat, Raji, K562, THP-1, HL-60, NCI-H929, rat kidney. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

PRMT5 (protein arginine N-methyltransferase 5) is an arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. PRMT5 specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 and Sm D3; such methylation is required for the assembly and biogenesis of snRNP core particles.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PRMT5
Applications Immunoprecipitation, Western Blot
Classification Monoclonal
Clone GT3610
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene PRMT5
Gene Accession No. O14744
Gene Alias 72 kDa ICln-binding protein; EC 2.1.1.125; histone-arginine N-methyltransferase PRMT5; HMT1 hnRNP methyltransferase-like 5; HRMT1L5; hypothetical protein; I79_013398; IBP72; Jak-binding protein 1; JBP1; PRMT5; protein arginine methyltransferase 5; protein arginine N-methyltransferase 5; Protein arginine N-methyltransferase 5, N-terminally processed; protein arginine N-methyltransferase 5-like; shk1 kinase-binding protein 1 homolog; Skb1; SKB1 homolog; SKB1Hs
Gene Symbols PRMT5
Host Species Mouse
Immunogen Recombinant protein encompassing a sequence within the center region of human PRMT5. The exact sequence is proprietary.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10419, 364382
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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