PRMT5 Mouse anti-Human, Clone: OTI2H3, lyophilized, TrueMAB™

Catalog No.	Quantity
50-166-8375	100 μg

Catalog No. 50-166-8375 Supplier OriGene Supplier No. CF807621

Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.

Specifications

• Antigen: PRMT5
• Applications: Immunohistochemistry (Paraffin)
• Classification: Monoclonal
• Clone: OTI2H3
• Conjugate: Unconjugated
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene: PRMT5
• Gene Accession No.: O14744
• Gene Alias: HRMT1L5, IBP72, JBP1, SKB1, SKB1Hs
• Gene Symbols: PRMT5
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 238-499 of human PRMT5 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10419
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG2a