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Invitrogen™ PRMT5 Polyclonal Antibody
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Catalog No. PIPA530383
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100 μL
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Catalog No. Quantity
PIPA530383 100 μL
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Catalog No. PIPA530383 Supplier Invitrogen™ Supplier No. PA530383
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, Jurkat, Raji. Predicted reactivity: Mouse (98%), Rat (98%), Zebrafish (85%), Japanese Medaka (86%), Xenopus laevis (91%), Pig (100%), Rhesus Monkey (100%), Chimpanzee (99%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

PRMT5 (protein arginine N-methyltransferase 5) is an arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. PRMT5 specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 and Sm D3; such methylation is required for the assembly and biogenesis of snRNP core particles.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PRMT5
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.49 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol; pH 7
Gene PRMT5
Gene Accession No. O14744, Q8CIG8
Gene Alias 72 kDa ICln-binding protein; EC 2.1.1.125; histone-arginine N-methyltransferase PRMT5; HMT1 hnRNP methyltransferase-like 5; HRMT1L5; hypothetical protein; I79_013398; IBP72; Jak-binding protein 1; JBP1; PRMT5; protein arginine methyltransferase 5; protein arginine N-methyltransferase 5; Protein arginine N-methyltransferase 5, N-terminally processed; protein arginine N-methyltransferase 5-like; shk1 kinase-binding protein 1 homolog; Skb1; SKB1 homolog; SKB1Hs
Gene Symbols PRMT5
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human PRMT5. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10419, 27374
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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