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Invitrogen™ PRMT6 Monoclonal Antibody (4B11F1C10)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA529504

Catalog No. PIMA529504


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Description

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human PRMT6/HRMT1L6.

Protein arginine N-methyltransferase 6 (PRMT6) PRMT6 demonstrates type I PRMT activity, capable of forming both omega-N monomethylarginine and asymmetric dimethylarginine derivatives on the recombinant glycine- and arginine-rich substrates. cts as a transcriptional coactivator of a number of steroid hormone receptors including ESR1, ESR2, PGR and NR3C1. Promotes fasting-induced transcriptional activation of the gluconeogenic program through methylation of the CRTC2 transcription coactivator. May play a role in innate immunity against HIV-1 in case of infection by methylating and impairing the function of various HIV-1 proteins such as Tat, Rev and Nucleocapsid protein p7.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

PRMT6
Monoclonal
Unconjugated
PRMT6
AW124876; BB233495; FLJ10559; FLJ51477; heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6; Histone-arginine N-methyltransferase PRMT6; HMT1 hnRNP methyltransferase-like 6; Hrmt1l6; PRMT6; PRMT-6; protein arginine methyltransferase 6; protein arginine N-methyltransferase 6
Mouse
Protein A
RUO
55170
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
ELISA, Western Blot
4B11F1C10
PBS with no preservative
Q96LA8
PRMT6
Recombinant Human PRMT6 protein (Met1-Asp375).
100 μL
Primary
Human
Antibody
IgG2b
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