Invitrogen™ PRMT6 Monoclonal Antibody (4B11F1C10)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA529504

Catalog No. PIMA529504

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human PRMT6/HRMT1L6.

Protein arginine N-methyltransferase 6 (PRMT6) PRMT6 demonstrates type I PRMT activity, capable of forming both omega-N monomethylarginine and asymmetric dimethylarginine derivatives on the recombinant glycine- and arginine-rich substrates. cts as a transcriptional coactivator of a number of steroid hormone receptors including ESR1, ESR2, PGR and NR3C1. Promotes fasting-induced transcriptional activation of the gluconeogenic program through methylation of the CRTC2 transcription coactivator. May play a role in innate immunity against HIV-1 in case of infection by methylating and impairing the function of various HIV-1 proteins such as Tat, Rev and Nucleocapsid protein p7.

Specifications

• Antigen: PRMT6
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: PRMT6
• Gene Alias: AW124876; BB233495; FLJ10559; FLJ51477; heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6; Histone-arginine N-methyltransferase PRMT6; HMT1 hnRNP methyltransferase-like 6; Hrmt1l6; PRMT6; PRMT-6; protein arginine methyltransferase 6; protein arginine N-methyltransferase 6
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 55170
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Western Blot
• Clone: 4B11F1C10
• Formulation: PBS with no preservative
• Gene Accession No.: Q96LA8
• Gene Symbols: PRMT6
• Immunogen: Recombinant Human PRMT6 protein (Met1-Asp375).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b