PRMT6 Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-157-2178	Bethyl Laboratories, Inc IHC00488T	10 μL
50-157-2177	Bethyl Laboratories, Inc IHC00488	100 μL

Description

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Bovine, Dog, Horse, Panda, Orangutan, Monkey, Gorilla, Chimpanzee, Chinese hamster, Naked mole ra

Protein arginine N-methyltransferase 6 (PRMT6) PRMT6 demonstrates type I PRMT activity, capable of forming both omega-N monomethylarginine and asymmetric dimethylarginine derivatives on the recombit glycine- and arginine-rich substrates. cts as a transcriptional coactivator of a number of steroid hormone receptors including ESR1, ESR2, PGR and NR3C1. Promotes fasting-induced transcriptional activation of the gluconeogenic program through methylation of the CRTC2 transcription coactivator. May play a role in innate immunity against HIV-1 in case of infection by methylating and impairing the function of various HIV-1 proteins such as Tat, Rev and Nucleocapsid protein p7.

Specifications

• Antigen: PRMT6
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Alias: FLJ10559, FLJ51477, HRMT1L6
• Immunogen: Between 325 and C-term
• Primary or Secondary: Primary
• Content And Storage: 4° C
• Gene: PRMT6

• Applications: Immunohistochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: Q6NZB1, Q96LA8
• Gene ID (Entrez): 55170, 99890
• Isotype: IgG
• Purification Method: Antigen affinity chromatography
• Product Type: Antibody