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Invitrogen™ PRMT6 Recombinant Rabbit Monoclonal Antibody (JE36-57)
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Catalog No. FEMA550821
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100 μL
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Catalog No. Quantity
FEMA550821 100 μL
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Catalog No. FEMA550821 Supplier Invitrogen™ Supplier No. MA550821
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Description

Rabbit Recombinant Monoclonal Antibody

Positive control: Human kidney tissue lysate, mouse kidney tissue lysate, mouse testis tissue lysate, rat kidney tissue lysate, rat testis tissue lysate, 293T cell lysate, HEK-293 cell lysate. Predicted band size: 42 kDa Subcellular Location: Nucleus.

Protein arginine N-methyltransferase 6 (PRMT6) PRMT6 demonstrates type I PRMT activity, capable of forming both omega-N monomethylarginine and asymmetric dimethylarginine derivatives on the recombinant glycine- and arginine-rich substrates. cts as a transcriptional coactivator of a number of steroid hormone receptors including ESR1, ESR2, PGR and NR3C1. Promotes fasting-induced transcriptional activation of the gluconeogenic program through methylation of the CRTC2 transcription coactivator. May play a role in innate immunity against HIV-1 in case of infection by methylating and impairing the function of various HIV-1 proteins such as Tat, Rev and Nucleocapsid protein p7.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PRMT6
Applications Western Blot
Classification Recombinant Monoclonal
Clone JE36-57
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene PRMT6
Gene Accession No. Q6NZB1, Q96LA8
Gene Alias AW124876; BB233495; FLJ10559; FLJ51477; heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6; Histone-arginine N-methyltransferase PRMT6; HMT1 hnRNP methyltransferase-like 6; Hrmt1l6; PRMT6; PRMT-6; protein arginine methyltransferase 6; protein arginine N-methyltransferase 6
Gene Symbols PRMT6
Host Species Rabbit
Immunogen Synthetic peptide within Human PRMT6 aa 191-240/375.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 295384, 55170, 99890
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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