Probenecid, 98%

Description

CAS: 57-66-9 | C13H19NO4S | 285.36 g/mol

It is a uricosuric drug, that is, it increases uric acid excretion in the urine. It is primarily used in treating gout and hyperuricemia. Probenecid was developed as an alternative to caronamide to competitively inhibit renal excretion of some drugs, thereby increasing their plasma concentration and prolonging their effects.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in water (partly miscible), solutions of alkali hydroxides,, ethanol (100 mM), acetone, chloroform, sodium hydroxide (1 M), DMSO (100 mM), methanol, dilute acids (practically insoluble), dilute alkalies, and ether (slightly soluble).

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Specifications

Chemical Identifiers

• CAS: 57-66-9
• Molecular Formula: C13H19NO4S
• Molecular Weight (g/mol): 285.36
• MDL Number: MFCD00038402
• InChI Key: DBABZHXKTCFAPX-UHFFFAOYSA-N
• Synonym: probenecid, 4-dipropylsulfamoyl benzoic acid, probenecid acid, probecid, benecid, benemid, benuryl, probalan, probenemid, probexin
• PubChem CID: 4911
• ChEBI: CHEBI:8426
• IUPAC Name: 4-(dipropylsulfamoyl)benzoic acid
• SMILES: CCCN(CCC)S(=O)(=O)C1=CC=C(C=C1)C(O)=O

• Melting Point: 198°C to 199°C
• Assay Percent Range: 0.98
• Quantity: 10 g
• Merck Index: 14,7754
• Solubility Information: Soluble in water (partly miscible),solutions of alkali hydroxides,,ethanol (100 mM),acetone,chloroform,sodium hydroxide (1 M),DMSO (100 mM),methanol,dilute acids (practically insoluble),dilute alkalies,and ether (slightly soluble).
• Formula Weight: 285.36
• Percent Purity: 98%
• Chemical Name or Material: Probenecid

Safety and Handling

Hazard Category	H302-H315-H319-H335
Hazard Statement	GHS H Statement H301-H315-H319-H335 Toxic if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
EINECSNumber	200-344-3
RTECSNumber	DG9400000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only