Invitrogen™ Procollagen I C-Peptide Monoclonal Antibody (04)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ BTE0020402

Catalog No. BTE0020402

Description

BTE 002-04-02 is specific for human native PICP from amniotic fluid. Crossreactivity to other species is not determined. BTE 002-04-02 has been successfully used ELISA procedures. NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL.

Collagen type I is present in soft connective tissue and bone where it represents approximately 90% of the organix matrix. Collagen type I is produced from procollagen when two teloterminal propeptides are digested from the procursor and released into the circulation. The propeptide levels can be measured in serum as indicators of collagen production. Elevated values of these propeptides in serum are found in patients with various bone metabolism defects. Procollagen type I C-terminal propeptide (PICP) has a molecular weight of approximately 100 kDa and the normal range in serum depends on age and sex.

Specifications

• Antigen: Procollagen I C-Peptide
• Classification: Monoclonal
• Concentration: 0.97 mg/mL
• Formulation: PBS with 15mM sodium azide; pH 7.4
• Gene Accession No.: P02452
• Gene Symbols: COL1A1
• Immunogen: PICP purified from second trimester amniotic fluid by affinity chromatography.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: ELISA
• Clone: 04
• Conjugate: Unconjugated
• Gene: COL1A1
• Gene Alias: Alpha-1 type I collagen; alpha1(I) procollagen; COL1A1; collagen alpha 1 chain type I; collagen alpha-1(I) chain; collagen alpha-1(I) chain preproprotein; collagen of skin, tendon and bone, alpha-1 chain; collagen type I alpha 1; collagen, type I, alpha 1; C-terminal Collagen; EDSC; OI1; OI2; OI3; OI4; PICP; pro-alpha-1 collagen type 1; Procol; Procollagen; type I proalpha 1; type I procollagen alpha 1 chain
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 1277
• Content And Storage: 4°C, store in dark
• Form: Liquid

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov