Invitrogen™ Procollagen I N-Peptide Monoclonal Antibody (C6)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA543883

Catalog No. PIMA543883

Description

Procollagen I N-Peptide Monoclonal Antibody for Western Blot, IHC (P)

Procollagen type I N-terminal propeptide (P1NP) is a specific marker of bone formation, reflecting the synthesis of type I collagen, which constitutes the major part of the bone matrix. P1NP is derived during the conversion of procollagen to collagen, produced by osteoblasts during bone formation. Its primary clinical application lies in the diagnosis and monitoring of metabolic bone diseases, particularly osteoporosis. In osteoporotic patients, P1NP levels can predict bone mineral density (BMD) responses to treatments like teriparatide and romosozumab. Low serum levels of P1NP are indicative of a high risk of BMD loss, providing a valuable tool for premenopausal women with systemic lupus erythematosus (SLE) and other conditions affecting bone health.

Specifications

• Antigen: Procollagen I N-Peptide
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: P02452
• Gene Symbols: COL1A1
• Immunogen: Recombinant protein Procollagen I N-Terminal Propeptide.
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: C6
• Conjugate: Unconjugated
• Gene: COL1A1
• Gene Alias: P1NP; Procollagen I N
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 1277
• Content And Storage: -20°C
• Form: Liquid

Safety and Handling

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